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Keisuke Imamura Selected Research

stearoyl-coenzyme A (stearoyl-CoA)

7/2017In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor.
1/2017Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents.
1/2017Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition.

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Keisuke Imamura Research Topics

Disease

2Colorectal Neoplasms (Colorectal Cancer)
07/2017 - 01/2017
1Neoplasms (Cancer)
07/2017
1Obesity
01/2017

Drug/Important Bio-Agent (IBA)

3stearoyl-coenzyme A (stearoyl-CoA)IBA
07/2017 - 01/2017
2T-3764518IBA
07/2017 - 01/2017
1EnzymesIBA
07/2017
1Fatty Acids (Saturated Fatty Acids)IBA
07/2017
1LipidsIBA
07/2017
1oleoyl-coenzyme AIBA
07/2017
1Stearoyl-CoA DesaturaseIBA
07/2017

Therapy/Procedure

1Therapeutics
07/2017